Lack of associations between betatrophin/ANGPTL8 level and C-peptide in type 2 diabetic subjects

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Lack of associations between betatrophin/ANGPTL8 level and C-peptide in type 2 diabetic subjects

BACKGROUND Betatrophin has been suggested as an inducer of β-cell proliferation in mice in addition to its function in regulating triglyceride. Recent data showed that betatrophin was increased in Type 2 Diabetes (T2D), however, its ability to induce insulin production has been questioned. We hypothesized that the increased betatrophin in T2D is not affecting insulin production from β-cells. To...

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C-Peptide and Vascular Complications in Type 2 Diabetic Subjects

Corresponding author: Seok Man Son Department of Internal Medicine, Pusan National University School of Medicine, and Diabetes Center and Endocrine Clinic, Pusan National University Yangsan Hospital, 20 Geumo-ro, Mulgeum-eup,Yangsan 626-770, Korea E-mail: [email protected] C-peptide is a small peptide comprised of 31 amino acids, with a short half-life of approximately 30 minutes. It was first ...

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Basal C-peptide Level as a Surrogate Marker of Subclinical Atherosclerosis in Type 2 Diabetic Patients

BACKGROUND Recent studies have revealed that C-peptide induces smooth muscle cell proliferation and causes human atherosclerotic lesions in diabetic patients. The present study was designed to examine whether the basal C-peptide levels correlate with cardiovascular risk in type 2 diabetes mellitus (T2DM) patients. METHODS Data was obtained from 467 patients with T2DM from two institutions who...

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ژورنال

عنوان ژورنال: Cardiovascular Diabetology

سال: 2015

ISSN: 1475-2840

DOI: 10.1186/s12933-015-0277-1